Creamy Artichoke Pasta Bake

Featured in: Vegetarian Picks

This comforting Italian-American bake combines al dente pasta with sautéed spinach and artichoke hearts, all bound together in a luxurious Parmesan cream sauce. The mixture is topped with buttered breadcrumbs and baked until golden and bubbling, creating a satisfying vegetarian main dish that serves four in just 50 minutes total.

Updated on Sun, 18 Jan 2026 13:03:00 GMT
Golden, bubbling Artichoke Pasta Bake fresh from the oven, served in a white dish with a golden breadcrumb crust. Pin
Golden, bubbling Artichoke Pasta Bake fresh from the oven, served in a white dish with a golden breadcrumb crust. | garlicgroove.com

My neighbor brought this to a potluck on a rainy October evening, and I ate three helpings before asking for the recipe. The artichokes were tangy and tender, the cream sauce clung to every piece of pasta, and that golden breadcrumb crust crackled under my fork. I made it the following weekend and burned the top because I got distracted by a phone call. Even then, my husband scraped the dish clean and asked when I'd make it again.

I started making this whenever friends came over because it looks impressive but requires no fancy technique. One time I forgot to buy spinach and used arugula instead, which added a peppery bite that everyone loved. The bubbling cheese and toasted breadcrumbs always draw people into the kitchen before I even call them to the table. It's become my go to for nights when I want to feel generous without spending hours at the stove.

Ingredients

  • Short pasta (penne, rigatoni, or fusilli): The ridges and tubes catch the creamy sauce perfectly, and cooking it just to al dente prevents it from turning mushy in the oven.
  • Artichoke hearts: Drain them well and pat dry if they're swimming in brine, otherwise the casserole can turn watery.
  • Fresh baby spinach: It wilts down to almost nothing, so don't be shy about packing it into the pan.
  • Yellow onion and garlic: Sautéing them first builds a sweet, aromatic base that makes the whole dish smell like home.
  • Heavy cream and whole milk: The combination gives you richness without being too heavy, and the milk keeps the sauce from breaking.
  • Freshly grated Parmesan cheese: Pre grated stuff doesn't melt as smoothly, and the flavor is nowhere near as sharp and nutty.
  • Olive oil: Just enough to get the onions translucent and fragrant without adding grease.
  • Dried Italian herbs, black pepper, salt, and nutmeg: Nutmeg is the secret, it deepens the cream sauce in a way you can't quite name but definitely notice.
  • Breadcrumbs and melted butter: This topping turns golden and crunchy, adding texture that makes every bite more interesting.

Instructions

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Prep the oven and dish:
Preheat to 190°C (375°F) and grease your baking dish generously so nothing sticks. I use butter for this because it adds a little extra flavor to the edges.
Cook the pasta:
Boil it in well salted water until just al dente, then drain and set aside. It will continue cooking in the oven, so undercooking slightly is key.
Sauté the aromatics:
Heat olive oil in a large skillet over medium heat, then cook the onion until soft and translucent, about 3 minutes. Add garlic and stir for another minute until fragrant.
Wilt the spinach and warm the artichokes:
Toss in the spinach and let it collapse into the pan, about 2 minutes. Stir in the quartered artichoke hearts and cook for another 2 minutes, then remove from heat.
Make the cream sauce:
In a saucepan, warm the cream and milk over medium low heat, then stir in Parmesan, Italian herbs, salt, pepper, and nutmeg. Keep stirring until the cheese melts and the sauce turns smooth and glossy, about 3 minutes.
Combine everything:
In a large bowl, mix the cooked pasta, sautéed vegetables, and cream sauce until every piece is coated. Transfer the mixture to your prepared baking dish and spread it evenly.
Add the topping:
Toss breadcrumbs with melted butter in a small bowl, then sprinkle evenly over the casserole. Add extra Parmesan on top if you want more cheese (I always do).
Bake until golden:
Slide the dish into the oven and bake for 20 to 25 minutes, until the top is golden and the edges are bubbling. Let it rest for 5 minutes before serving so the sauce thickens slightly.
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Measure spices, liquids, and baking ingredients accurately for consistent results in cooking and baking.
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Close-up of creamy Artichoke Pasta Bake with tender pasta, wilted spinach, and marinated artichoke hearts in a rich sauce. Pin
Close-up of creamy Artichoke Pasta Bake with tender pasta, wilted spinach, and marinated artichoke hearts in a rich sauce. | garlicgroove.com

The first time I served this to my in laws, my mother in law asked if I'd taken a cooking class. I laughed and told her I'd just followed my nose and tasted as I went. She took the leftovers home in a container and texted me two days later asking for the recipe. That's when I knew this dish had officially made it into my permanent rotation.

How to Store and Reheat

I always make extra because this keeps beautifully in the fridge for up to four days. Cover it tightly with foil or transfer it to an airtight container, and reheat individual portions in the microwave or the whole dish in a 180°C (350°F) oven for about 15 minutes. The breadcrumbs lose a little crunch, but a quick run under the broiler brings them back to life.

Simple Swaps and Variations

If you can't find baby spinach, kale works just as well, though you'll want to chop it finely and cook it a minute longer. I've also stirred in sun dried tomatoes and roasted red peppers for a pop of color and sweetness. Once I used orecchiette instead of penne, and the little ear shapes held onto the sauce in the most delightful way.

Pairing and Serving Suggestions

This pairs beautifully with a crisp white wine like Pinot Grigio or a simple green salad dressed with lemon and olive oil. I like to serve it straight from the baking dish at the table because it stays warm longer and feels more communal. A crusty baguette on the side is perfect for mopping up any creamy sauce left on your plate.

  • Add a handful of fresh basil or parsley on top just before serving for a burst of color and freshness.
  • If you want more protein, toss in shredded rotisserie chicken or cooked white beans.
  • For a lighter version, swap half the cream for more milk and reduce the butter in the topping.
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Artichoke Pasta Bake served in a ceramic dish, garnished with fresh parsley and extra Parmesan, ready for dinner. Pin
Artichoke Pasta Bake served in a ceramic dish, garnished with fresh parsley and extra Parmesan, ready for dinner. | garlicgroove.com

This dish has a way of turning ordinary weeknights into something worth sitting down for. Make it once, and I promise it'll become one of those recipes you return to again and again.

Recipe Questions

Can I prepare this dish ahead of time?

Yes, you can assemble the casserole up to 8 hours ahead. Cover and refrigerate, then bake for an additional 5-10 minutes to account for the cold temperature. Add the breadcrumb topping just before baking for best texture.

What pasta shapes work best for this bake?

Short, tubular pasta like penne, rigatoni, or fusilli are ideal as they hold the cream sauce well. Avoid long pasta like spaghetti, which can be difficult to mix and serve from a casserole dish.

How do I prevent a watery casserole?

Make sure to drain the canned artichoke hearts thoroughly and squeeze excess moisture from the spinach after cooking. Don't overcook the pasta—al dente is essential. If your dish seems wet before baking, drain any excess liquid from the bottom.

What wines pair well with this dish?

Crisp white wines like Pinot Grigio, Sauvignon Blanc, or Vermentino complement the creamy sauce beautifully. Their acidity cuts through the richness and cleanses the palate between bites.

Can I substitute the heavy cream?

You can use Greek yogurt or sour cream for a lighter version, though the sauce will be slightly less rich. Avoid low-fat cream, as it may curdle when heated. Add Greek yogurt off the heat and stir gently to prevent separation.

How should I store leftovers?

Store covered in the refrigerator for up to 3 days. Reheat gently in a 160°C (320°F) oven for 15-20 minutes, covering with foil to prevent the top from browning too much. You can also freeze for up to 2 months; thaw overnight before reheating.

Creamy Artichoke Pasta Bake

Creamy casserole with tender pasta, spinach, and artichoke hearts baked in a rich Parmesan sauce. Ready in 50 minutes.

Prep duration
20 min
Cook duration
30 min
Complete duration
50 min


Complexity Easy

Heritage Italian-American

Output 4 Portions

Dietary requirements Vegetarian

Components

Pasta

01 12 oz short pasta such as penne, rigatoni, or fusilli

Vegetables

01 14 oz canned artichoke hearts, drained and quartered
02 4 oz fresh baby spinach
03 1 small yellow onion, finely chopped
04 2 cloves garlic, minced

Sauce

01 1 cup heavy cream
02 1/2 cup whole milk
03 1 cup freshly grated Parmesan cheese, plus extra for topping
04 1 tablespoon olive oil
05 1 teaspoon dried Italian herbs
06 1/2 teaspoon freshly ground black pepper
07 1/2 teaspoon salt
08 1/4 teaspoon ground nutmeg

Topping

01 1/2 cup breadcrumbs
02 2 tablespoons unsalted butter, melted

Directions

Step 01

Prepare the oven and baking dish: Preheat oven to 375°F. Lightly grease a 2-quart baking dish with butter or cooking spray.

Step 02

Cook the pasta: Bring a large pot of salted water to a boil. Add pasta and cook until al dente according to package directions. Drain and set aside.

Step 03

Sauté aromatics and vegetables: Heat olive oil in a large skillet over medium heat. Add chopped onion and sauté for 3 minutes until softened. Add minced garlic and cook for 1 minute until fragrant.

Step 04

Wilt spinach and add artichokes: Add baby spinach to the skillet and cook for 2 minutes until fully wilted. Stir in drained artichoke hearts and cook for another 2 minutes. Remove from heat.

Step 05

Prepare the cream sauce: In a saucepan, combine heavy cream and whole milk over medium-low heat. Warm gently, then stir in grated Parmesan, Italian herbs, salt, pepper, and nutmeg. Continue stirring for approximately 3 minutes until cheese is completely melted and sauce reaches a smooth consistency.

Step 06

Combine pasta with vegetables and sauce: In a large mixing bowl, combine cooked pasta, sautéed vegetable mixture, and cream sauce. Stir until all components are evenly coated and distributed. Transfer to the prepared baking dish.

Step 07

Prepare and apply topping: In a small bowl, combine breadcrumbs with melted butter and toss until evenly moistened. Sprinkle the breadcrumb mixture evenly over the casserole surface. Add additional grated Parmesan if desired.

Step 08

Bake until golden: Place in preheated oven and bake for 20 to 25 minutes until the top is golden brown and the casserole is bubbling around the edges. Remove from oven and allow to rest for 5 minutes before serving.

Necessary tools

  • Large pot for pasta cooking
  • Large skillet for vegetable preparation
  • Saucepan for cream sauce
  • 2-quart baking dish
  • Mixing bowls for combining ingredients
  • Microplane or box grater for Parmesan cheese

Allergy details

Review each ingredient for potential allergens and speak with a healthcare provider if you're uncertain about anything.
  • Contains wheat gluten from pasta
  • Contains dairy from heavy cream, milk, butter, and Parmesan cheese
  • May contain egg if using egg-based pasta
  • May contain sulfites in certain marinated artichoke preparations

Nutrition breakdown (per portion)

These values are provided as estimates only and shouldn't replace professional medical guidance.
  • Energy: 570
  • Fat: 29 g
  • Carbohydrates: 56 g
  • Protein: 19 g